Sometimes, the right support is all you need to reach your weight loss goals.
Medications to assist with weight loss is becoming one of the go-to options for individuals wanting to lose weight and keep fit. There are several forms of weight loss medications which includes pills, injections, or even medical devices.
Choosing what fits you best might be difficult due to the large variety.
This blog seeks to highlight some of the most popular drugs for weight loss. Alongside, various prescribed medications as well as treatments will also be listed to assist you in achieving your desired weight.
What Is Weight Loss Medication?
Weight Loss medications are drugs developed to assist individuals in losing weight by suppressing appetite, blocking some forms of fat, or aiding in better insulin usage. Some of them are prescribed weight loss medications, and some are available over the counter.
You might find these drugs as:
- Oral weight loss medications (pills)
- Fast weight loss pills (for short-term use)
- Weight loss shots (injectable drugs)
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Not all medications are right for everyone, so it’s best to consult a doctor before starting any treatment.
7 Top Weight Loss Drugs to Know
Here are some of the most popular weight loss drug options used today:
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1. Tirzepatide (Zepbound / Mounjaro)
Tirzepatide is a new and exciting medication for weight loss prescription. Sold under Zepbound and Mounjaro, it’s approved for both obesity and type 2 diabetes.
How It Works:
- Activates two hormones (GLP-1 and GIP)
- Curbs appetite and helps control blood sugar
Why People Like It:
- Shown to help patients lose a lot of weight over time
- Good for long-term results
Side Effects: Nausea, constipation, and rarely, pancreatitis or gallbladder issues.
Price: About $1,060/month (with discount programs available)
Weight loss shots, names as Zepbound, are great for those who prefer injections over pills.
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2. Contrave (Naltrexone + Bupropion)
Contrave is a prescribed weight loss medication that targets the brain to reduce cravings.
How It Works:
- Combining drugs used for addiction and depression
- Reduces appetite and emotional eating
Why People Like It:
- Helps control food cravings
- A unique option among prescription weight loss tablets
Side Effects: Headaches, nausea, constipation, risk of seizures.
Price: $700–$800/month (assistance available)
3. Orlistat (Xenical / Alli)
One of the only FDA-approved oral weight loss medications. Available as Xenical (prescription) or Alli (OTC).
How It Works:
- Blocks about 30% of fat from being absorbed by your body
Why People Like It:
- Doesn’t affect your brain
- Budget-friendly
Side Effects: Oily stools, stomach cramps, gas—especially if you eat too much fat.
Price: Xenical ~$800/month; Alli < $60/month
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4. Phentermine
Phentermine is one of the fast weight loss pills doctors use for short periods.
How It Works:
- Suppresses appetite by releasing brain chemicals
Why People Like It:
- Very effective for quick results
- Affordable option
Side Effects: Dry mouth, insomnia, increased heart rate. Not for long-term use.
Price: Around $30-$40/month (generic)
5. Semaglutide (Wegovy / Ozempic)
Semaglutide is a game-changer. Known by Wegovy (weight loss) and Ozempic (diabetes).
How It Works:
- Mimics the GLP-1 hormone
- Makes you feel full longer and slows digestion
Why People Like It:
- Users lost up to 15% of their body weight in studies
- Works well with lifestyle changes
Side Effects: Nausea, diarrhea, rare risk of kidney or pancreas issues.
Price: $1,300–$1,500/month (discounts may apply)
One of the most effective weight loss RX drugs today.
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6. Liraglutide (Saxenda)
A daily injectable prescribed weight loss medication.
How It Works:
- Works like Semaglutide, but taken daily
- Reduces hunger and helps regulate blood sugar
Why People Like It:
- Helps many people manage weight long-term
Side Effects: Nausea, vomiting, concerns about pancreatitis or thyroid cancer
Price: $1,200–$1,400/month
7. Qsymia (Phentermine + Topiramate)
This combination medication offers a double approach to weight loss.
How It Works:
- Phentermine decreases appetite
- Topiramate increases fullness
Why People Like It:
- Effective for people who need extra help
- Taken once daily as an oral weight loss medication
Side Effects: Tingling, insomnia, dry mouth, birth defects (avoid during pregnancy)
Price: $210–$280/month
Why Medication Alone Isn’t Enough
Even the best prescription weight loss tablets won’t do much without a healthy lifestyle. These medications work best when combined with:
- A Healthy Diet:
- Eat real, whole foods: fruits, vegetables, lean meats, whole grains
- Limit processed and high-fat foods
- Drink plenty of water
- Regular Exercise:
- Aim for at least 150 minutes of movement per week
- Include both cardio and strength training
- Behavior Changes:
- Watch for emotional eating
- Practice portion control
- Get support from a therapist or nutritionist if needed
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Final Thoughts: Which Weight Loss Medication Is Right for You?
Choosing the right weight loss medication depends on your body, your goals, and your health history.
If you prefer pills, go for oral weight loss medications like Contrave, Orlistat, or Phentermine.
If you need something stronger or long-term, injections like Semaglutide, Liraglutide, or Tirzepatide may work better. These top weight loss drugs offer real help when lifestyle changes alone aren’t enough.
Your doctor can help you decide which medication for weight loss prescription fits your needs. Always follow their guidance and never self-prescribe.
Quick Recap:
- Tirzepatide and Semaglutide are newer options with great results
- Contrave and Qsymia help curb cravings and appetite
- Phentermine offers short-term, fast weight loss support
- Orlistat is a budget-friendly, fat-blocking pill
These weight loss RX drugs can give you the boost you need, but success comes from daily habits, not just pills.
With the right plan, a trusted doctor, and some commitment, you can take charge of your health and reach your weight goals.